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Transcatheter aortic valve replacement in severe symptomatic aortic stenosis

Jutta Bergler-Klein
Published in : HAMDAN MEDICAL JOURNAL ; Vol 5, No 1 (2012)
DOI : 10.7707/hmj.v5i1.111


Calcific aortic stenosis (AS) is a progressive disease increasingly found in elderly patients. Rapid aortic valve replacement (AVR ) is recommended as class I indication in symptoms development in severe AS because of the high mortality associated with lack of intervention.  As patients age, however, comorbidities also increase and pose a barrier to conventional surgery owing to prohibitive perioperative risk.

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Bonow RO, Carabello BA, Kanu C, et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2006; 114:e84–e231.

Carabello BA, Paulus WJ. Aortic stenosis. Lancet 2009; 373:956–66.

Leon MB, Smith CR, Mack M, et al. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 2010; 363:1597–607.

Reynolds MR, Magnuson EA, Lei Y, et al.; Placement of Aortic Transcatheter Valves (PARTNER) investigators. Health-related quality of life after transcatheter aortic valve replacement in inoperable patients with severe aortic stenosis. Circulation 2011; 124:1964–72.

Reynolds MR, Magnuson EA, Wang K, et al. Cost effectiveness of transcatheter aortic valve replacement compared with standard care among inoperable patients with severe aortic stenosis: results from the PARTNER trial (cohort B). Circulation 2012 [Epub ahead of print].

Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 2011; 364:2187–98.

Welt FG, Davidson MJ, Leon MB, Eisenhauer AC. Transcatheter aortic valve replacement. Circulation 2011; 124:2944–8.

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