Hamdan Medical Journal (previously the Journal of Medical Sciences)

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Relationship between Cognitive Impairment and Depressive Symptoms

Uzma Irfan Siddiqui, Shamalia Khalid
Published in : Journal of Medical Sciences ; Vol 4, No 3 (2011)
DOI : 10.2174/1996327001104030122

Abstract


The purpose of the study was to assess association between depressive symptoms and different domains of the cognitive status in patients with acute ischemic stroke and to identify cognitive domains that significantly correlated with the presence of depressive symptoms. The study comprised 40 acute ischemic stroke patients (14 women and 26 men) aged 45-78 years (± SEM 55.6 yrs.), with 8-16 years of education ((± SEM 13 years). Beck’s Depression Inventory (BDI) was used to assess depressive symptoms whereas the cognitive status was evaluated using a comprehensive neuropsychological testing battery which measures performance in different cognitive domains. The following domains were evaluated: visualconstructive performance in two dimensions and executive function, language, immediate recall, delayed recall, attention, divergent reasoning. The multiple regression analysis was applied. The results showed the overall regression model to be significant [R= 0.601; R = 0.362; F (7.62) =5.031; p<0.001]. The language domain was found to be a significant partial predictor of depression, with poorer performance in this domain correlating with a higherprevalence of depressive symptoms.

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