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Familial haemophagocytic lymphohistiocytosis

Ammar MH Shehadeh
Published in : HAMDAN MEDICAL JOURNAL ; Vol 6, No 2 (2013)
DOI : 10.7707/hmj.v6i2.240


Haemophagocytic lymphohistiocytosis (HLH) is a rare, but potentially fatal, disease that occurs when normal histiocytes and lymphocytes become overactive and commonly occurs in infancy. Two forms of the disease have been described: primary and secondary. This article reports twins who were less than 2 years old at the time of presentation and who had clinical symptoms of primary (familial) HLH, which was diagnosed by a contributory pathological bone marrow test.

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