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The magnitude of home hoarding and self drug prescriptions and their effect on bacterial resistance to amoxicillin in Hail, Saudi Arabia

I Abuqurayn, A Al-Abdli, N Al-Tamimi, A Babiker, M Alaraj
Published in : HAMDAN MEDICAL JOURNAL ; Vol 8, No 4 (2015): Supplement Issue
DOI : 10.7707/hmj.569


Introduction: Amoxicillin is one of the most common antibiotics prescribed in Hail, Saudi Arabia. Misuse and self-prescription of drugs may influence the bacterial response leading to drug resistance.

Objectives: To evaluate home hoarding of drugs and the misuse of drugs, and investigate subsequent bacterial resistance to amoxicillin.

Materials and methods: A randomized local population sample of 374 participants were included in the study. A revised direct interviewing questionnaire was distributed and mouth swabs were obtained from 19 patients with a documented upper respiratory tract infection following prescription of amoxicillin antibiotic as a treatment. Bacterial cultures were then performed to monitor the efficacy of amoxicillin by the antibiotic sensitivity test.

Results: The average age of participants ranged from 20 to 40 years. Amoxicillin was an effective drug against almost all organisms detected in swab cultures, but to variable extents. The study revealed that 41% of the participants tended to keep drugs at home to use them again according to their needs, while 29% tended to get rid of unused drugs. Forty per cent of people self-prescribed drugs. Twenty-two per cent of people increased the dose of the drug when they did not feel better while 60% committed to the prescribed dose.

Conclusions: There was no detection of resistance in the samples that were obtained; however, there was a variable response. The majority of cases studied were using drugs without doctor or health care prescriptions.

Acknowledgements: Dr Alhazimi for supervising this project.


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