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Haemophagocytic lymphohistiocytosis and the challenge of early diagnosis: a case report

Hoda Mohamed Hammoda, Mahmoud Mohamed Marashi, Hesham Abdalla Mohamed Abdalla, Mahmod EL Shahat Awad Makhlof, Manal Sayed Rezzek
Scheduled to Publish in : HAMDAN MEDICAL JOURNAL ; Future Issues
DOI : 10.7707/hmj.775

Abstract


Hemophagocytic lymphohistiocytosis (HLH) is an uncommon, life-threatening hyperinflammatory Syndrome with massive tissue destruction secondary to hypercytokinemia and excessive activation of lymphocytes and macrophages due to abnormal, ineffective energizing of the immune system. A high index of suspicion is necessary for early diagnosis. We report a case of Hemophagocytic Lymphohistiocytosis in a 66-year-old lady presented with fever, pancytopenia, and hepatosplenomegaly.

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References


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