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Year : 2021  |  Volume : 14  |  Issue : 3  |  Page : 138-141

Thromboprophylaxis causing spontaneous bleeds in COVID patients

Department of General Surgery, Rashid Hospital, Dubai, UAE

Correspondence Address:
Samreen Kidwai
Villa U4, District 9, Jumeirah Parks, Dubai
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/hmj.hmj_20_21

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COVID-19 is an ongoing pandemic that was identified in December 2019 in Wuhan, China. Patients admitted to the hospital with COVID-19 present with many coagulation abnormalities, precipitating a hypercoagulable state which exposes them to thrombosis for which they receive thromboprophylaxis therapy with enoxaparin. Over the course of this therapy, some patients develop spontaneous bleeding episodes in different regions of the body of varying degrees and sometimes require radiological angioembolisation to control the bleed. This case series sheds light on three patients who were admitted in Rashid Hospital, Dubai, UAE, with COVID-19 and developed spontaneous bleeds. Amongst the three patients, two of them developed retroperitoneal bleed and one patient developed a chest wall haematoma. One of them underwent radiological intervention (angioembolisation), while the other two underwent conservative management and were monitored for haemodynamic changes. There are limited studies demonstrating the correlation between high dose of enoxaparin and bleeding episodes amongst COVID-19 patients. However, we advise the need for further guidelines and data to advocate the relation between enoxaparin and bleeding episodes.

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